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Vol. 3, Issue 1, pages ​15-23
DOI: ​​​​https://doi.org/10.35252/jspir.2022.1.003.1.03
Highly porous porcine xenograft utilized in bone augmentation procedures: case reports with clinical, histological and histomorphometrical evaluation.
Belleggia F, Filetici P, Tagariello G, Nicoletti F, Dassatti L
Abstract
Purpose: The aim of this report was to evaluate clinically, histologically and histomorphometrically a new highly porous porcine cancellous xenograft.
Case Report: A porcine xenograft (Zcore™) was used to treat 3 patients requiring the use of a bone graft: patient A required a horizontal GBR with a simultaneous sinus lift, patient B required a socket preservation after lower canine extraction, patient C required a mandibular horizontal GBR for the first molar implant rehabilitation. Healing was uneventful for all the interventions and, after bone graft maturation, re-entry was scheduled after 8, 3 and 7 months for patient A, B and C respectively. At implant insertion, two specimens were harvested from patient A, and 1 specimen was taken either from patient B and C. All implants healed uneventfully. Histological sections showed xenograft particles integrated in newly formed bone. Histomorphometric analysis for patient A revealed a 60.2% of bone marrow/connective tissue and 39.8% of mineralized fraction in the first specimen, while the second specimen revealed a 58.1% of bone marrow/connective tissue and 41.9% of mineralized fraction. For patient B the specimen revealed a 61.4% of bone marrow/connective tissue and a 38.6% of mineralized fraction. For patient C the specimen revealed a 52.1% of bone marrow/connective tissue and a 47.9% of mineralized fraction.
Conclusion: The use of a highly porous porcine xenograft allowed greater empty space for new bone growth, and a successful implant osseointegration. The values of histomorphometric analysis highlight a very good new bone formation for all the interventions.
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  • ABOUT
    • Founder's Message
    • Copyright
    • Advertising
    • Permissions
    • Technical File
    • Editorial status
    • Peer Review Process
    • Ethical Policies >
      • Human and Animal rights
      • Conflict of Interest and Source of Funding
      • Guarantee of Impartiality in the Peer Review Process
      • Scientific Misconduct
    • Contact
  • Aims and Scope
  • Instructions For Authors
    • Publication charges
    • Peer Review Process
    • Ethical Policies
    • Complaints and appeals
    • Paper Submission
  • All ISSUES
    • 2019 - Volume 1 >
      • Issue 1
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    • 2020 - Volume 2 >
      • Issue 1
    • 2022 - Volume 3 >
      • Issue 1
  • Editorial Board
  • For Editors and Reviewers
    • Conflicts of Interest
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    • Call for Reviewers